Carlos Sainz topped second practice in Singapore ahead of his teammate Charles Leclerc in the Italian team’s second 1-2 of the day.
George Russell ended up in third place ahead of Fernando Alonso and his teammate Lewis Hamilton.
Red Bull suffered a mixed session with Sergio Perez in P7 just ahead of his team mate Max Verstappen in eighth place.
At the green light, a flurry of cars ventured onto the track under the lights in Singapore for the one-hour FP2 session.
Williams driver Logan Sargeant set the first flying lap time of the second practice session with a 1:36.897. His effort was quickly beaten by many drivers, including Sainz, who topped the timesheets after five minutes.
Ferrari held a 1-2 with Leclerc in second, just in front of Hamilton, during the first running at night of the weekend.
Most of the field ran the medium tyres in the opening 10 minutes, including the two Ferraris. Lance Stroll slotted into third place, half a second slower than Sainz’s 1:34.150.
Alonso broke the 1:34 barrier, achieving a 1:33.964 before the Spaniard was usurped by both Ferrari’s
Alex Albon complained of losing power from the final turn and promptly returned to the pits in the all-new Gulf livery on the Williams. The Thai would not return to the track for the remainder of the session because of a power unit problem.
Hamilton improved to fifth place for Mercedes, a sizeable seven-tenths slower than the pace-setting Sainz on the same yellow sidewall medium tyre.
Verstappen suffered rear locking over the Anderson Bridge and aborted his lap while sitting in a lowly ninth place.
Albon jumped out of his car, costing him valuable track time as the Wiliams team worked to diagnose the issue with his Williams FW45.
Japanese driver Yuki Tsunoda broke into the top three for AlphaTauri, setting a 1:33.483 than Leclerc, who held the quickest time with 20 minutes gone.
The Monegasque and other drivers bolted on the grippier soft tyres to his Ferrari as qualifying became the teams’ focus.
Sainz retook the top spot with a 1:32.120 after his first run on the soft tyre, fractionally ahead of his teammate, Alonso, who found himself half a second down on the two front runners.
Hamilton usurped his old rival, setting a 1:32.4, but remained four-tenths slower than the pacesetter halfway through the one-hour session.
The newly revamped Marina Bay circuit proved a real challenge as Sargeant ran wide at the final turn, and Kevin Magnussen brushed the wall earlier in the lap.
Mercedes’ Russell changed his front torsion bars during FP2 and slotted into P5, two-tenths behind his teammate Hamilton.
Both Haas cars sat in the top 10, with Magnussen just ahead of Valtteri Bottas and his teammate Nico Hulkenberg.
With 25 minutes to go, both Red Bulls floundered outside the top five on a weekend where they could clinch the Constructors’ title.
Perez struggled with rear locking with 20 minutes to go before the Mexican edged ahead of Verstappen in P7, as the two Ferraris continued to lead the way.
During the final quarter of an hour, the 10 teams switched their focus to long runs.
Verstappen requested a new steering wheel as his current wheel lacked grip on the right side, in a disrupted session for the world champion.
In the final 10 minutes, most cars circulated to get some long run data at the end of Friday running.